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Welcome - Let's Get Personal!
After a long time of thinking about it (and a long time spent procrastinating), I've decided to resurrect the blog. So I've slapped on a new coat of paint, added a few new gew-gaws, and I'm off to the races.
Sort of.
The blog is now actually an experiment of sorts. I'm waist-deep in writing my thesis, which is a risk prediction system that is able to sit at the heart of a personalized medicine system. It's fascinating work and I'm learning incredible amounts both about the mechanism of making a prediction and about what extra steps are necessary to make an algorithm clinically relevant and doctor friendly.
But the prediction side isn't the only part of personalized medicine that's fascinating. It has the potential to drastically change the way medical care is delivered, but there are a number of hurdles to clear first. Some of those are technological, and some of those are at the heart of my thesis project. But other hurdles are policy issues, economic issues, ethical issues, and privacy issues. I have no way of addressing them (other than VERY briefly) in my thesis, both because they're too far afield, and because I have little expertise in those areas.
I like to think broadly about things, however, and I think that this topic is too important to be considered in isolation. This is something that needs to be discussed publicly, both to allay people's fears and also to take advantage of their wisdom. So that's what I'll be trying to do. I'm going to begin by defining some terms and then we'll see where that takes me.
As I said, this is an experiment, so this will be a little different than a typical blog. The posts will tend to be longer and somewhat less frequent. For now the plan is to publish on Mondays and Thursday, but that may change in the future. For me this blog is going to serve two purposes: 1) to keeping up writing while I'm actually doing the work of the thesis (I've just spent a month writing the first two chapters of my thesis, and I know how much constant practice improves writing, so I want to give myself that practice), and 2) to serve as a testing grounds for ideas to put into a publication on the policy of personalized medicine. I'd love to hear input and comments, so please send me an email (my address is in the sidebar).
Interesting Papers
Don Quixote and the quest for personalized medicine.Pubmed | Connotea
Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.
Pubmed | Connotea
Francis Collins interview. Departing U.S. genome institute director takes stock of personalized medicine.
Pubmed | Connotea
Challenges to the translation of genomic information into clinical practice and health policy: Utilization, preferences and economic value.
Pubmed | Connotea
From protein-disease associations to disease informatics.
Pubmed | Connotea
Update on the molecular diagnosis of endocrine tumors: toward -omics-based personalized healthcare?
Pubmed | Connotea
Development of a Large-Scale De-Identified DNA Biobank to Enable Personalized Medicine.
Pubmed | Connotea
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure.
Pubmed | Connotea
Clinical utility of a genetic susceptibility test for severe chronic periodontitis: a critical evaluation.
Pubmed | Connotea
Gene-expression assays: new tools to individualize treatment of early-stage breast cancer.
Pubmed | Connotea
All Connotea papers tagged "personalized medicine"
All of Reagan's Connotea papers
Blogroll
Bioinformatics.orgNodal Point
Flags and Lollipops
Postgenomic
The Gene Sherpas
Eye on DNA
Genetics & Health
The Personal Genome
Omics! Omics!
Science Roll
Genetic Future
The DNA Network
My Biotech Life
Medicine 2.0
Respectful Insolence
The Epistasis Blog

testing the comments
Came here via Tangled Bank. Glad I found you! We can always use more genetics bloggers. :) Best of luck on the thesis.